herbal wound healing

the popularity and evidence of continued use clearly indicates that there are still lessons to be learned from traditional practices. maintaining homeostasis is critical for the survival of the organism; hence, skin needs and possesses a robust and effective repair mechanism. the underlying cause of the wound is often used to describe the wound: diabetic foot ulcers, venous leg ulcers, arterial leg ulcers, and pressure ulcers. traditional medicine is often described by practitioners of “modern” (western) medicine using sceptical terms such as “alternative,” “nonconventional,” “indigenous,” and “complementary,” when in fact many of the techniques and practices of “modern” medicine are little different from traditional practices when it comes to wounds. arctium lappa is also reported to regulate cell adhesion and gene expression in canine dermal fibroblasts, affecting the wnt/β-catenin signalling pathway, known to be a key regulator of wound healing [52]. the root of astragalus propinquus is a common tcm for the treatment of urinary retention and oedema [54]. in the philippines, blumea balsamifera is known as sambong and is used as a diuretic. the heartwood of caesalpinia sappan is well known for its qualities as a dye and has been used in tcm to improve blood circulation and reduce oedema and pain [98]. less widely known, carthamus tinctorius also has a long history as an ingredient in tcm formulations for the treatment of blood disorders.




cinnamomum cassia is a commonly used spice and flavouring agent, and the bark of cinnamomum cassia is also used to increase blood circulation and as an analgesic [147]. curcumin, an active substance found in the root of curcuma longa and a member of the ginger family, has long been used as a medicine and as food seasoning [167]. analyses of the data concluded that the improved wound healing was due to the antibacterial, proproliferative, and promigration activity of the entada phaseoloides extracts [182]. the dried root of paeonia suffruticosa is commonly applied to cracked skin to assist healing and relieve pain [219]. panax ginseng is one of the most popular medicinal plants consumed in china, japan, korea, and eastern siberia to improve thinking, concentration, and memory. emodin [1,3,8-trihydroxy-6-methyl-anthraquinone], an anthraquinone derived from the roots of rheum officinale, has been shown to act as a ligand for ppar-γ and interact with hsp90 and androgen receptors, in part explaining its therapeutic benefit for chronic diseases [271]. in mouse studies, the oral administration of polysaccharides isolated from sanguisorba officinalis is claimed to stimulate wound contraction, reduce the time required for reepithelization (wound closure), increase collagen synthesis, and improve angiogenesis [296]. luteolin, a flavonoid present in the leaves, has been demonstrated to contribute to the medicinal value of wedelia trilobata, conferring neuroprotective, anticancer, antioxidant, and immunomodulatory activities [311]. fractionated ethanolic extracts from the leaves of wedelia trilobata and assayed them in vitro [310]. also shared are many of the same biological targets and pathways; many of these are also key events in the mammalian wound healing cascade.

the medicinal plants used in wound healing treatment in traditional persian medicine could be a good topic for further in vivo and clinical research. other active principles such as triterpenes, alkaloids, and flavonoids have proven to be effective in this process.10 traditional systems of medicine provide valuable information on natural remedies. in the 5 traditional books that we searched, a total number of 65 herbs that were used in traditional persian medicine for their wound-healing properties could be identified (table 1).

there were also 9 herbs that were studied for the 3 mechanisms of action related to wound healing and showed positive effect but their wound-healing properties have not been studied yet. in this work, we revealed the herbal remedies for wound healing in traditional persian medicine and reviewed their possible mechanisms of action. declaration of conflicting interests: the authors declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

4. traditional use of medical plants in wound healing 4.1. aloe vera 4.2. arctium lappa 4.3. astragalus propinquus and rehmannia glutinosa 4.4. ampelopsis they include boswellia sacra flueck, cinnamomum camphora (l) j presl, heracleum persicum desf ex fischer, physalis alkekengi l, polygonum aviculare l, raphanus the use of honey in wound management dates back to many centuries. honey has been used to treat, .

clinical studies have shown that neem extract prevents inflammation and subsequently increases wound healing [5]. neem leaf extracts and oil people have been healing with plants for generations and you’ll find more than one list of plants that heal wounds. three herbs often cited medicinal plants such as curcuma longa (l.), terminalia arjuna, centella asiatica, bidens pilosa, aloe barbadensis, and rauwolfia serpentine, . herbsaloe (aloe vera), as a cream or gel. calendula (calendula officinalis), or pot marigold, as an ointment or a tea applied topically. marshmallow (althaea officinalis) as a topical ointment to help wounds heal and fight inflammation.tea tree oil (melaleuca alternifolia) as oil or cream.

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