in mice, berbamine was demonstrated to increase neutrophil and lymphocyte counts, apparently by stimulating bone marrow stem cell differentiation (li et al., 1994). bone marrow from healthy people and some with aplastic anemia were cultured with a total saponin extract of p. ginseng (gao et al., 1992). its polysaccharides have been shown to offset the marrow suppressive effects of cyclophosphamide in mice (hui et al., 2006).
subcutaneous injection of special preparations of viscum album (european mistletoe) have been shown to elevate granulocyte-macrophage colony stimulating factor levels in cancer patients in a controlled clinical trial (schultze et al., 1991). clearly, much more work is needed to determine which western herbs could be useful in treating people with anemia or other states of bone marrow depression. gao rl et al: effect of total saponins of panax ginseng on hematopoietic progenitor cells in normal human and aplastic anemia patients (in chinese), zhongguo zhong xi yi jie he za zhi (chin j integration trad west med) 12(5):285-7, 1992. hui mk et al: polysaccharides from the root of angelica sinensis protect bone marrow and gastrointestinal tissues against the cytotoxicity of cyclophosphamide in mice, int j med sci 3:1-6, 2006. li sy et al: effect of berbamine on blood and bone-marrow stem cells of cyclophosphamide-treated mice, int j immunopharmacol 16(3):245-9, 1994. ning l et al: effect of components of dang-gui-bu-xue decoction on hematopenia, zhongguo zhong yao za zhi 27:50-53, 2002. niu yp et al: effects of ginsenosides rg1 and rb1 on proliferation of human marrow granulocyte-macrophage progenitor cells, zhongguo shi yan xue ye xue za zhi 9:178-80, 2001. schultze jl et al: demonstration of specifically sensitized lymphocytes in patients treated with an aqueous mistletoe extract (viscum album l.), klin wochenschr 69:397-403, 1991. tang q et al: influence of shenmai injection on blood serum tumor necrosis factor and bone marrow cd34+ cell’s apoptosis of chronic aplastic anemia patient (in chinese), zhongguo zhong yao za zhi 30:1296-8, 2005. yang k et al: clinical trial of berbamine in 405 leukopenia patients (in chinese), yao hsueh tung pao 17(4):21-22, 1982.
pancytopenia is a health condition in which there is a reduction in the amount of leucocytes, erythrocytes and thrombocytes. the clinical observations include reduced number of leucocytes, erythrocytes and thrombocytes in the blood . benzene damages the bone marrow and therefore stops the haematopoiesis and in turn the production of cells, which causes pancytopenia. it is said that the hormones also play a very important role in the management of pancytopenia . it stimulates the process of erythropoiesis and is used to increase the productions of erythrocytes in the body. in the treatment of pancytopenia these stem cells are used so that the body can produce normal cells with the aid of pluripotent stem cells. few plants and herbs are under research for the treatment of pancytopenia. also, it regulates the plasticity of the monocytes and in turn of the macrophages . the causes still remain the same as that of pancytopenia in general. it also stimulates the production of haemoglobin and erythrocytes in anaemia .
as the survival of bone marrow is increased, it can directly enhance the production of erythrocytes, leucocytes and thrombocytes and benefit in the treatment of pancytopenia. a cross-sectional study of the clinical profile and aetiological spectrum of pancytopenia in a tertiary care centre. hormones and the bone marrow: panhypopituitarism and pancytopenia in a man with a pituitary adenoma. an unusual cause of pancytopenia in a patient with systemic lupus erythematous. clinical effects of blood donor characteristics in transfusion recipients: protocol of a framework to study the blood donor–recipient continuum. effects of mongolia astragalus on early cardiac and nephritic function in patients of hypertension with metabolic syndrome. microb pathog 2014;66:48–56.10.1016/j.micpath.2013.12.005search in google scholar nih national centre for complementary and integrative health. int immunopharmacol 2005;5:219–229.10.1016/j.intimp.2004.09.028search in google scholar pubmed nih national centre for complementary and integrative health. j ethnopharmacol 2002;81:393–397.10.1016/s0378-8741(02)00117-4search in google scholar 77. ahmadiani a, javan m, semnanian s, barat e, kamalinejad m. anti-inflammatory and antipyretic effects of trigonella foenum-graecum leaves extract in the rat. asian pac j trop biomed 2011;1:330–333.10.1016/s2221-1691(11)60055-5search in google scholar 86. national center for biotechnology information. (wheatgrass) in prevention and treatment of chronic diseases: an overview.
current therapies for pancytopenia include bone marrow stimulant drugs, blood transfusion and bone marrow transplant. berberis and mahonia species plants have been utilized, particularly in tcm, as bone marrow stimulants. research conducted in china has currently, bone marrow stimulant drugs like epoetin alfa (epogen, procrit), filgrastim (neupogen), pegfilgrastim (neulasta), sargramostim (, related conditions, related conditions, herbs for bone marrow, pancytopenia with normal bone marrow, pancytopenia bone marrow.
current therapies for pancytopenia include bone marrow stimulant drugs, blood transfusion and bone marrow transplant. the current therapies are according to the literature reviewed, herbal extracts as stimulants of hmsc proliferation and differentiation show outstanding results and are bone marrow stimulants certain drugs — including colony-stimulating factors, such as sargramostim (leukine), filgrastim (neupogen) and, chinese herbs for bone marrow, bone marrow cleansing cancer, how long can you live with pancytopenia, pancytopenia criteria, diet for pancytopenia, bone marrow transplant, pancytopenia treatment cost, pancytopenia natural treatment, pancytopenia treatment drugs, aplastic anemia holistic treatment.
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