i have some ideas, but i’m not sure which of them are likely to actually work in practice as i’m having trouble digging through the mass of info (most of which is huge lists of herbs that either have small amounts of a c.10î¼m constituent, or even herbs that are just suspected of having that mechanism). there are a few that seem likely to work for which i can’t find any positive reports for verification, and some which have negative reports (indicating either lack of effect on brain mao or sidle-effects/lack of selectivity). a non-selective maoi might work ok for me, but i haven’t tried it yet and i’m hoping for a reliable solution, so i’d like to keep that as a backup plan an incomplete list of what i’ve been considering (i’d try to continue working on it, but at the rate i’m going i’d be researching for several more days and still not have a decision – did i mention my adhd causes significant perseveration? i’m not sure if comt inhibition will help me; it seems reasonable but i don’t have past experience and i’m trying to get something reliable.
spirulina or other bg algae – active (phycocyanin) isn’t very powerful (c.10î¼m) but i think there’s a lot of it in extracts cordyceps – in the study that calls it an maoi, they got c.50% inhibition by mixing extract and brain homogenate at a 1:10 ratio hordenine – seems way too short-acting; however, i wonder if high doses would have a biphasic elimination profile that makes it last longer, and if in this case the high dose would cause too many side effects if anyone can help me out with other ideas or verification on what i’ve listed, based either on your experience or deeper knowledge of the subject, i’d be very appreciative. if you want a source relating to something specific, ask and i’ll dig up what i found on it. – researchgate seems to have taken the full text for this down just in the last few days. edit: i’m not sure why i couldn’t load the fulltext earlier today, it’s still there.
phellodendron contains berberine, which can inhibit dna topoisomerase and kill bacteria. piperine is hepatotoxic in high amounts. kava is widely peganum harmala seeds (syrian rue) is the first potent natural maoi that comes to mind. potentially anything with harmine and its https://psychonautwiki.org/wiki/maoi – here’s your list. https://integrativepharmacology.com/2021/04/25/natural-mao-inhibitors/ (whoa, quercetin, mao inhibitor supplements, mao inhibitor supplements, natural mao inhibitors foods, natural maoi, how to reduce monoamine oxidase naturally.
i was looking into some of these natural ones that have some research on them. turmeric. black pepper. cinnamon. vanilla. nutmeg. licorice. naturally occuring monoamine oxidase inhibitors (maois)?. hey, first post on this subreddit and reddit in general. my question to r/psychopharmacology is st john’s wort has some maoi and catecholamine re-uptake inhibiting compounds; kava has some maoi activity and gaba agonism/modulation; and, maoi supplements reddit, syrian rue, maoi nootropics, phellodendron mao-b, green tea mao inhibitor, pterostilbene maoi, amur cork tree dopamine, selegiline nootropics depot, safinamide nootropic, emoxypine withdrawal reddit.
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